Mixed Gonadal Dysgenesis

A type of defective gonadal development in patients with a wide spectrum of chromosomal mosaic variants. Their karyotypes are of partial sex chromosome monosomy resulting from an absence or an abnormal second sex chromosome (X or Y). Karyotypes include 45,X/46,XX; 45,X/46,XX/47,XXX; 46,XXp-; 45,X/46,XY; 45,X/47,XYY; 46,XYpi; etc. The spectrum of phenotypes may range from phenotypic female to phenotypic male including variations in gonads and internal and external genitalia, depending on the ratio in each gonad of 45,X primordial germ cells to those with normal 46,XX or 46,XY constitution.

Also Known As:

Gonadal Dysgenesis, Mixed

Urogenital Diseases: 126
- Urogenital Abnormalities: 76
  - Disorders of Sex Development: 730
    - Gonadal Dysgenesis: 516
      - Mixed Gonadal Dysgenesis: 66
    - Sex Chromosome Disorders of Sex Development: 3
      - Mixed Gonadal Dysgenesis: 66
- Female Urogenital Diseases and Pregnancy Complications
  - Female Urogenital Diseases
    - Urogenital Abnormalities: 76
      - Disorders of Sex Development: 730
        Gonadal Dysgenesis: 516
        Mixed Gonadal Dysgenesis: 66
        Sex Chromosome Disorders of Sex Development: 3
        Mixed Gonadal Dysgenesis: 66
- Male Urogenital Diseases
  - Urogenital Abnormalities: 76
    - Disorders of Sex Development: 730
      - Gonadal Dysgenesis: 516
        Mixed Gonadal Dysgenesis: 66
      - Sex Chromosome Disorders of Sex Development: 3
        Mixed Gonadal Dysgenesis: 66
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Congenital Abnormalities: 25723
  - Chromosome Disorders: 136
    - Sex Chromosome Disorders: 5
      - Sex Chromosome Disorders of Sex Development: 3
        Mixed Gonadal Dysgenesis: 66
  - Urogenital Abnormalities: 76
    - Disorders of Sex Development: 730
      - Gonadal Dysgenesis: 516
        Mixed Gonadal Dysgenesis: 66
      - Sex Chromosome Disorders of Sex Development: 3
        Mixed Gonadal Dysgenesis: 66
- Inborn Genetic Diseases: 11939
  - Chromosome Disorders: 136
    - Sex Chromosome Disorders: 5
      - Sex Chromosome Disorders of Sex Development: 3
        Mixed Gonadal Dysgenesis: 66
Endocrine System Diseases: 968
- Gonadal Disorders: 30
  - Disorders of Sex Development: 730
    - Gonadal Dysgenesis: 516
      - Mixed Gonadal Dysgenesis: 66
    - Sex Chromosome Disorders of Sex Development: 3
      - Mixed Gonadal Dysgenesis: 66

Jesús Benítez-Granados Selected Research

Jesús Benítez-Granados Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure